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This medicine includes codeine which may induce addiction if you're taking it continually for more than three days. This can provide you with withdrawal signs within the medicine if you halt having it.May possibly reduce the analgesic effect of tramadol hydrochloride tablets and/or precipitate withdrawal indicators.Respiratory despair would be the
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teofilin (lek za lečenje astme i drugih problema sa disanjem), jer može da oslabi dejstvo diazepama;Nakon primene leka savetuje se da pacijent ostane u ležećem položaju najmanje jedan sat. Osim u hitnim slučajevima, druga osoba treba da bude prisutna tokom intravenske primene. Takođe je neophodno da bude dostupna oprema za reanimaciju.Kod pa
Trajanje terapije treba da je što je moguće kraće, u zavisnosti od indikacije (videti odeljak four.2). Stanje pacijenta se mora proceniti nakon perioda ne dužeg od 4 nedelje, a potom u redovnim vremenskim intervalima, da bi se procenila potreba za daljim lečenjem, posebno ukoliko pacijent više nema simptome.Significant: Due to danger of misus